Keywords
Abstract
In the Russian Federation in the first decade of the XXI century, the prevalence of tuberculosis is characterized by certain stabilization in some regions, but overall the situation remains very tense, due to the low level of prevention in adults, worsening of clinical forms of the disease, increase in the number of patients with bacterial excretion, including multidrug-resistant strains. In the study the multivariate data analysis has been performed covering: medical history, social status, clinical and radiological characteristics of patients with tuberculosis of respiratory organs: 72 patients had multi-drug resistance of the causative agent, 99 - extensively drug-resistant Mycobacterium tuberculosis. It is proved that patients with extensively drug resistant pathogen more «severe» in social terms - low treatment compliance, lack of social support, unhealthy habits that worsen prognosis of the disease and reduce effectiveness of therapy. From medical perspective this group of patients requires more intensive treatment (long-term detoxification and patho genetic therapy) and, most importantly, a properly sized specific treatment, as the set of effective drugs for these patients is currently very limited.Keywords: lung tuberculosis, drug resistance, multivariate analysis